Consistent with this, we found a positive correlation of CXCR7 expression with a gene stromal signature built from overlapping genes from the TCGA mesenchymal subtype and the Tothill C1 (tumor desmoplasia) subtype samples that were positively correlated with mesenchymal markers and ECM remodeling (Verhaak et al., 2013; Yang et al., 2017). Here, ACKR3 is linked to neoplasm.