Using ERα‐positive TOV2295 and TOV3133G cells generated from human ovarian carcinomas (Letourneau et al., 2012), we also found a similar expression profile with the upregulation of CXCR7 and CXCL11 in response to estrogen, which further validates the distinct regulation in OC cells (Fig. 2D). This evidence concerns the gene ESR1 and ovarian carcinoma.