Despite its sensitivity to diagnose PPCM [15, 25, 47, 61–63] and cost-effectiveness, natriuretic peptides (brain natriuretic peptide “BNP” and N-terminal-proBNP “NT-proBNP”) are, unfortunately, non-specific markers for a variety of other cardiovascular pathologies, including myocardial ischemia, preeclampsia, pulmonary emboli, and, most notably, heart failure [15, 47, 64, 65]. The gene discussed is NPPB; the disease is heart failure.