CD40LG and erythema multiforme: The frequency of positive reactions for C6 IgM, C6 IgG, and VlsE IgM in the EM/HGA patients was significantly (p <0.05) higher than in EM patients (both at the baseline and at all times of recovery); differences in the frequency of OspC IgM detection in EM/HGA and EM patients were not statistically significant.