We labeled and screened 9 plasma membrane RTKs on these cells, which included two established GBM biomarkers, EGFR and insulin-like growth factor receptor (IGFR) (Sangar et al., 2014), and angiogenic signaling biomarkers: VEGFRs, PDGFRs, NRP1, and Tie2 (Carmeliet and Jain, 2000, 2011; Ferrara, 2002; Ferrara and Kerbel, 2005; Dudley, 2012). The gene discussed is EGFR; the disease is glioblastoma.