The cell-by-cell analysis and mixture modeling suggests that this ensemble average does not capture the subpopulations having high-PDGFR plasma membrane localization: 66 and 16% of mouse tumor EC-like cell membrane had ~23,400 PDGFRα and ~19,800 PDGFRβ, respectively (Figure 2F). The gene discussed is PDGFRA; the disease is neoplasm.