As shown in Figure 3(a), compared to the PAO1-infected WT RAW264.7, macrophages with pLVX-gp91phoxKDshRNA2 responded to PAO1 infection as low gp91phox expression and decreased nuclear NF-κB p65 level and its phosphorylation on Ser536. The gene discussed is NFKB1; the disease is infection.