In humans, splicing alterations of the sarcomeric genes, TNNT2 (troponin T2), TNNI3 (troponin I3), MYH7 (myosin heavy chain 7), and FLNC (filamin C gamma) were observed in both DCM and hypertrophied myocardium. The gene discussed is MYH7; the disease is familial dilated cardiomyopathy.