Multivariable linear regression analysis further verified a significant relationship between IL-34 level and NT-proBNP level (β = 0.171, P < 0.001) after adjusting for age, sex, BMI, history of hypertension, history of DM, and levels of hsCRP, hemoglobin, albumin, HbA1c, as well as eGFR (Table 2). The gene discussed is IL34; the disease is Hypertension.