As showed in our results, compared with both the non-CAD control group and CAD group, serum IL-34 levels were significantly elevated in subjects with ICM, correlated with NT-proBNP level, echocardiography parameters, including LVEF, LVEDD, LVESD and LAD, as well as with NYHA functional class, suggesting its function in the process of HF. This evidence concerns the gene IL34 and coronary artery disorder.