AKT1 and type 2 diabetes mellitus: Three of the four differentially expressed miRNA between the healthy and T2DM group 1 clusters overlapped with the differentially expressed miRNA between the two diabetes clusters, namely miR-29a, miR-17, and miR-24, which were predicted to target 24 genes within the PI3K/Akt pathway; similarly, miR-29a showed the highest degree of regulation of these miRNA (Figure 4D).