LPA and diabetes mellitus: HoFH and LDL ≥7.8 mmol/l (≥300 mg/dl), or non-HDL ≥8.5 mmol/l (≥330 mg/dl)HeFH with LDL ≥7.8 mmol/l (≥300 mg/dl), or non-HDL ≥8.5 mmol/l (≥330 mg/dl), and 0–1 risk factorsHeFH with LDL ≥5.2 mmol/l (≥200 mg/dl), or non-HDL ≥6 mmol/l (≥230 mg/dl) and ≥2 risk factors, or Lp(a) ≥50 mg/dlHeFH with LDL ≥4.1 mmol/l (≥160 mg/dl), or non-HDL ≥4.9 mmol/l (≥190 mg/dl) and very high risk (established CAD, other CVD, or diabetes)