This suggests that although neurogenesis and post-stroke recovery may occur in tandem, this may be coincidental, with recovery being more directly related to the upregulation of a variety of growth-promoting factors such as BDNF and GAP43 (Rossi et al., 2006; Ploughman et al., 2009; Clarkson et al., 2011; Mizutani et al., 2011; Cook et al., 2017). This evidence concerns the gene GAP43 and stroke disorder.