TSC1 and Tremor: The early onset of tremors in Tsc1cKO mutants at P10 and death around P15-P20 is very similar to that observed in Contactin-associated protein 1 (Caspr1; Bhat et al., 2001) or Contactin (Boyle et al., 2001), or NfascNF155 mutants (Pillai et al., 2009) combined with reduced nerve conduction properties, which prompted us to analyze the myelinated nerve organization and whether axonal domains were compromised in myelinating glia-specific Tsc1 mutants.