Since oxidation of KCNB1 is associated to both amyloidosis and oxidative stress, we assessed the levels of hyperphosphorylated tau in the brains of 1-year-old mice by IHC, using an antibody that detects phosphorylated tau at Ser199 (Fig. 9a, b), and phosphorylated tau at Ser356 (Fig. 9c). The gene discussed is MAPT; the disease is amyloidosis.