HMGB1 and cancer: For the association between rs1360485 in HMGB1 and cancer risks, OR1 (1.02, 95%CI: 0.80, 1.28; P=0.90), OR2 (1.07, 95%CI: 0.94, 1.22; P=0.31), and OR3 (1.08, 95%CI: 0.92, 1.62; P=0.36) were all statistically insignificant, which suggested no potential association between rs1360485 and risk of cancer.