We found that 3 mg/kg/day of Ang II in BMT mice were sufficient to induce aortic aneurysm rupture at a level with non-BMT mice receiving 0.8 mg/kg/day Ang II, in comparison to 0.8, or 1.5 mg/kg/day of Ang II in BMT mice (Fig. 1C). This evidence concerns the gene AGT and aortic aneurysm.