Whilst performing BMT into irradiated ApoE−/− mice, to generate bone marrow chimeric animals to assess leukocyte gene function in AAA, we observed that BMT mice infused with Ang II at 0.8 mg/kg/day did not develop aortic aneurysms in comparison with non-irradiated mice receiving this dose. This evidence concerns the gene APOE and aortic aneurysm.