Between days 3 and 10 of Ang II infusion, 7 out of 16 non-BMT ApoE−/− mice died from aneurysm rupture, but no deaths occurred in BMT mice, indicating that BMT may confer protection from Ang II-induced aortic aneurysm rupture (Fig. 1A). Here, APOE is linked to aortic aneurysm.