MFSD8 and neuronal ceroid lipofuscinosis 7: A CLN7-lacZ gene trap hypomorphic mouse model was created first that recapitulates some of the neuropathological features of human CLN7 disease including accumulation of storage in CNS and periphery, along with reactive gliosis, however these mice show no evidence of motor decline nor premature death (Damme et al., 2014).