Mean MoM levels of GDM women ranged from 0.70–1.17 for PAPP-A and 0.78–1.13 for free β-hCG and 0.97–1.22 and 0.97–1.15 for PAPP-A and free β-hCG in normoglycemic women, respectively. The gene discussed is PAPPA; the disease is gestational diabetes.