Logistic regression analysis considering age (≥50 years),TB (≥5×ULN), HBeAg negative status,IgM anti-HBc levels(≥10 S/CO),and HBVDNA levels(<5.0 log10 IU/mL) at admission was employed to determine independent predictors of AHB-ALF.TB≥5×ULN and HBeAg negative status were independently associated with AHB progression to ALF (Table 2). This evidence concerns the gene KRT88P and tuberculosis.