FLT1 and renal cell carcinoma: However, later it was shown to have a potent inhibitory effect on the tyrosine kinase activity of receptors such as VEGFR1/3 and PDGR [4], allowing its use in several pathologies including Hepatocellular Carcinoma, Thyroid Carcinoma and Renal Cell Carcinoma (RCC) (for a review see [5].