Although rs7566605 was not significantly associated with obesityin our study population, we cannot rule out the involvement of <GENE>INSIG2</GENE> in <DISEASE>obesity</DISEASE> related traits as we found a significant association of another tag SNP in <GENE>INSIG2</GENE> with both BMI and ABDCIR. The gene discussed is INSIG2; the disease is obesity due to melanocortin 4 receptor deficiency.