NOS1 and infarction: Two weeks after MI, nNOS-KO mice experienced a high death rate (Figure 7(a)), augmented infarction area (Figures 7(b) and 7(c)), increased cardiac hypertrophy (Figures 7(b) and 7(d)), fibrosis (Figures 7(e) and 7(f)), and cell apoptosis (Figures 7(g) and 7(h)).