SOD1 and arthritic joint disease: To examine whether Δ9-THC/sesame oil can attenuate the oxidative stress known to be involved in the pathogenesis of arthritis, levels of MDA, a major biomarker of lipid peroxidation and activities of antioxidant enzymes such as SOD and catalase as well as concentration of nonenzymatic antioxidant GSH, were determined in liver homogenates.