The experimental research showed that its ability to induce apoptosis in cancer cells or cancer stem cells (CSCs) was possibly attributed to the mitochondrial-related B-cell lymphoma- (Bcl-) 2 regulation [10, 11], extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) [12], or Wnt [13] signaling pathways, as well as cell cycle arrest [14, 15]. This evidence concerns the gene WNK2 and cancer.