Based on infections in C57BL/6 and LysM-GFP mice, neutrophils (CD11b+Ly6C+Ly6G+LysM−GFPHi cells) were found in this study to be the main innate immune cell type recruited rapidly to the dermal site of infection, a feature that was inherent to the biting related tissue damage and irrespective of trypanosome presence. Here, ITGAM is linked to infection.