Levels of the ADAM10 species did not correlate with the core AD biomarkers in NADC, while in AD samples, higher Aβ42 levels correlated with lower ADAM10f levels (R = 0.43; p = 0.027), but not correlations were observed with the levels of sADAM10 species (Additional file 4: FigureS3). The gene discussed is ADAM10; the disease is Alzheimer disease.