Some studies have revealed that IL-1β + 3954C/T is related to an increased risk of MI in Caucasian populations.[15,17] However, Daraei et al[19] demonstrated that the TT genotype of the IL-1β + 3954C/T polymorphism was associated with a significant MI-protective effect in an Asian population, and Wang et al[16] showed that IL-1β + 3954C/T was not correlated with MI risk in a Chinese population. Here, IL1B is linked to myocardial infarction.