When stratified by cancer type, increased CIP2A expression had an unfavorable impact on the OS of patients with lung cancer (pooled HR = 1.842, 95% CI 1.286–2.638, P = 0.001) and colorectal cancer (pooled HR = 1.897, 95% CI 1.108–3.249, P = 0.020). This evidence concerns the gene CIP2A and lung cancer.