Low PON1 activity has been reported in previous studies as one of the leading factors causing atherosclerosis and myocardial infarction (Ayub et al., 1999; James et al., 2000; Mackness et al., 2002; van Himbergen et al., 2005; Bryk et al., 2005; Gur et al., 2006). Here, PON1 is linked to atherosclerosis.