Localization of the Tspo mRNA in Grade III invasive carcinoma (NST) was observed in the cytoplasm of tumour cells arranged as nests and collagen fibres of the fibrotic stroma and in the nuclei and cytoplasm of lymphocytes located between the tumour and stroma, indicating the presence of a mononuclear infiltrate (Figure 7E,F). The gene discussed is TSPO; the disease is neoplasm.