Some patients exhibit elevated liver enzymes (ALT ≥50 U/l), hypoproteinemia and reduced plasma lipid levels, elevated cholestasis parameters (GGT ≥40, hyperbilirubinemia), thrombocytosis (≥450.00/μl), leukocytosis (≥15.000/μl), and/or anemia (Figure 4). The gene discussed is GPT; the disease is thrombocytosis disease.