PPARG and metabolic syndrome: In n3-polyunsaturated fatty acids (PUFA) depleted rats, an animal model of metabolic syndrome, a decrease in AQP7 protein levels was observed without any modification in Aqp7 mRNA levels [possibly due to the lack of PPARγ activation concomitant to PUFA depletion, as PPARγ normally activates the transcription of AQP7 (Kishida et al., 2001)] and glycerol transport (Portois et al., 2012b).