At this early time-point, we found no difference in the apoptotic cell fraction and cell cycle distribution of BM and spleen ALL cells between IFN and control mice (Supplementary Fig. 3a–d), while the proliferation rate, as measured by EdU incorporation, was lower in the BM, but not the spleen, of IFN mice (Supplementary Fig. 3e, f, *p < 0.05, Mann–Whitney). This evidence concerns the gene IFNA1 and acute lymphoblastic leukemia.