Expression analysis showed that increased ERRα expressions exhibited a significant positive correlation with the Gleason scores in ERG-positive but not ERG-negative prostate cancer patients and higher ERRα was also shown in metastatic prostate cancer tissues (Fig. 1d, e; Supplementary Fig. S1c), and associated with shorter survival of prostate cancer patients [26]. The gene discussed is ESRRA; the disease is prostate carcinoma.