Among miRNAs which regulate epigenetic enzymes,miR-483-5p regulates MeCP2 levels and there is an inverse correlation of miR-438-5p and MeCP2 levels in developing human brains and fibroblasts from Beckwith-Wiedemann syndrome patients56, as revealed in MSC from BOS patients in our experimental setting. Here, MECP2 is linked to Beckwith-Wiedemann syndrome.