BRAF and colorectal cancer: On the basis of previous reports,6, 7, 8, 9, 10, 11 we investigated the prognostic associations of KRAS and BRAF mutations in relation to MSI status by pooling data from an extended set of the QUASAR 2 and Australian cohorts, including an additional 676 colorectal cancers from QUASAR 2 and 362 stage II or III colorectal cancers from the Australian cohort (n=1732).