MUC16 and cancer: Additionally, the Schwartz group [19] found that the simultaneous use of the LSA and CA-125 concentrations enhances significantly the sensitivity for Ovarium cancer detection, from 76% for CA-125 alone to 84% when using information of the two markers combined, with cut off values of LSA > 24 mg/dL and CA-125 > 60 U/mL.