Five days of treatment of the GBM mice with Vehicle (PBS with MIg pretreatment), or CCP with either MIg pretreatment (CCP group) or NK1.1Ab pre-treatment (CCP + NK1.1 group) (Fig. 2a) caused a 200% increase in activated (NKp46(+)) NK cells in the GBM tumor of the CCP- but not CCP + NK1.1Ab-treated mice (Fig. 2b and c). The gene discussed is NCR1; the disease is glioblastoma.