AIF1 and neoplasm: Our IHC analysis demonstrated that the GBM tumor in the Vehicle-treated mice at death harbored high levels of activated STAT3 (P-Y705-STAT3 or P-STAT3) (Additional file 1: Figure S1A and B), but the scar tissue sections from the CCP-treated and rescued mice displayed a 98% suppression of P-STAT3 (Additional file 1: Figure S1A and B) in the Iba1(+) (activated) TAM.