Furthermore, by using an in vivo growth assay mouse model, we found that the volume and weight of tumor with DU145 cells stably overexpressing the cytoplasmic tail of embigin showed significantly smaller than those of tumor with GFP-control cells (Figure 5E), whereas overexpressed embigin inversely increased tumor volume and weight, and Ki67-positive cells (Figure S2A,B, Supplementary Materials). The gene discussed is EMB; the disease is neoplasm.