GJB1 and hepatocellular carcinoma: To address such a question, we have previously demonstrated that Cx32 protein is not localised in plasma membrane but in the Golgi-apparatus in human HuH7 hepatoma cells and that accumulation of Cx32 protein in the Golgi-apparatus reinforces different malignant phenotypes of HuH7 cells, resulting in the induction of metastasis in the mice xenografted with HuH7 cells overexpressing Cx32 protein in the Golgi-apparatus [17,18].