Heterozygous mutations of TWIST1 (MIM# 601622) result in Saethre‐Chotzen syndrome (SCS; MIM# 101400) and typical features include coronal craniosynostosis, hypertelorism, ptosis, low frontal hairline, blocked tear ducts, and small dysmorphic ears (El Ghouzzi et al., 1997; Howard, et al., 1997). This evidence concerns the gene TWIST1 and Saethre-Chotzen syndrome.