WNK2 and thymoma: Once activated by secreted proteins of the signaling component of the FGF family, tyrosine kinase FGF receptors are able to phosphorylate specific tyrosine residues that thereafter mediate interaction with cytosolic adaptor proteins and the RAS-MAPK (rat sarcoma—mitogen-activated protein kinase), PI3K-AKT (phosphoinositide 3-kinase–Ak thymoma), PLCγ (phosphoinositide phospholipase Cγ), and STAT (signal transducers and activators of transcription) intracellular signaling pathways [45].