In summary, we have built on single gene associations detected in GWAS of SZ to show that genes that are functionally related to SATB2 and the NuRD complex during neocortical development or are targeted by SATB2 in the pre- and postnatal brain are enriched for common variants associated with SZ and EA, and for rare variants that increase risk of SZ and other neurodevelopmental disorders. The gene discussed is SATB2; the disease is neurodevelopmental disorder.