Morphologic abnormalities due to abnormal differentiation in myeloid cells are also encountered in congenital, cyclic, dysgranulopoietic neutropenia cases [7,10,66,68] with or without the WAS, GFI-1, and G6PC3 mutations [1,7], in myelodysplastic syndrome, and in a number of non-malignant disorders [16,67]. This evidence concerns the gene G6PC3 and myelodysplastic syndrome.