In summary, carcinogenesis or tumour progression in certain cancers can be significantly inhibited by up‐regulation of m6A modification induced by overexpression of the tumour suppressor “writer” (METTL3 and METTL14) and SAM and silencing of the oncogene “eraser” (FTO and ALKBH5) and “reader”(YTHDF2). The gene discussed is METTL3; the disease is cancer.