HBXIP is commonly identified as an oncogene and exerts a profound effect on breast cancer.89, 90 A recent study has found that there was a strongly positive association between HBXIP and METTL3.91 Overexpression of HBXIP could significantly elevate the expression of METTL3 in breast cancer tissues and vice versa. Here, METTL3 is linked to breast cancer.