In fact, a meta‐analysis revealed that various FTO SNPs were associated with different cancers such as endometrial cancer, pancreatic cancer and breast cancer dependent on or independent of BMI adjustment.54 In addition, aberrant expression or mutation of FTO has been shown to have an intimate link with prostate cancer,55 endometrial cancer56 and breast cancer.57, 58, 59, 60 However, the potential role of FTO as a demethylase remains a nascent yield to be explored. This evidence concerns the gene FTO and familial pancreatic carcinoma.