On the mechanism, IFNγ elicits regression of the tumor vasculature, leading to arrest of blood flow and subsequent collapse of tumors, which is like non‐hemorrhagic necrosis in ischemia and unlike hemorrhagic necrosis induced by TNFα.25 This finding suggests that IFNγ slow tumor growth via induction of tumor ischemia. The gene discussed is TNF; the disease is neoplasm.