The pharmaceutical drug Captopril, which is currently used to treat hypertension and congestive heart failure because of its function as angiotensin-converting enzyme (ACE) inhibitor, has been known to be able to prevent structural changes to the heart, when administered after radiation exposure (20 Gy), but there is no evidence seen in its ability to prevent the decline in cardiac function (87). Here, ACE is linked to hypertensive disorder.