LRP6 and coronary artery disorder: ROS in bone marrow MSCs and serum level of malonaldehyde (MDA), a stable end product of lipid peroxidation, were significantly elevated in HFD-fed mice relative to CHD-fed mice (Figure S1a and S1b), indicating possible involvement of oxPLs in the reduction in osteoblast differentiation ability and LRP6 level in MSCs.