Expression levels of Cyclin-Dependent Kinase (CDK-1, CDK-2, and CDK-6) were also significantly down-regulated in U87TRAF3IP2KD cells (-9.3, -2.4, and -2.1, respectively; Supplementary Table 1), indicating that silencing TRAF3IP2 affects glioblastoma cell cycle progression. The gene discussed is CDK1; the disease is glioblastoma.