TRAF3IP2 and glioblastoma: Our data show that both wild type U87 and U118 cells display high sphere-forming ability during the 24- to 96-hour study period (Figure 1E), an effect markedly reduced by TRAF3IP2 knockdown (U87TRAF3IP2KD and U118TRAF3IP2KD; 20 spheroids/cell type were randomly selected for measurement; triplicate experiments; P<0.05), demonstrating the role of TRAF3IP2 in sphere-forming potential of malignant glioblastoma cells.