KLF5 and acute lymphoblastic leukemia: After Klf5 gene deletion induction (Figure 2F, arrows), we found that Klf5 expression (Figure 2E) extended the survival of Klf5∆/∆ leukemic mice (Figure 2F), which supports the role of Klf5 as a tumor suppressor in p190 BCR-ABL transformed B-ALL.