Also, comparing these same AVA subtype concentration ratios between BALF and serum within each group, as well as between individual subjects, demonstrated that the proportion of antibodies to the C-terminus was higher in the BALF of sarcoidosis patients (irrespective of HLA-DRB1*03 carriage) but not in HCs, again implicating the sarcoid lung as a site of heightened proportional secretion of antibodies to the vimentin C-terminus. Here, HLA-DRB1 is linked to sarcoidosis.