IL6 and Alzheimer disease: Besides, as mentioned in the previous paragraphs, elevated levels of hs-CRP, and its principal downstream inducers, including IL6, has been repeatedly found to be cross-sectionally associated with classically described CNS disorders such AD, vascular dementia, and RTT (Zuliani et al., 2007; Koyama et al., 2013; Cortelazzo et al., 2014).